This section provides an overview for dehydroacetic acids as well as their applications and principles. Also, please take a look at the list of 11 dehydroacetic acid manufacturers and their company rankings. Here are the top-ranked dehydroacetic acid companies as of November, 2024: 1.ChemScence, 2.ATAMAN Kimya A.S. INC., 3.Neuchem.
Table of Contents
Dehydroacetic acid, a derivative of the heterocyclic compound pyrone, is denoted by the chemical formula C8H8O4. It is predominantly utilized in its sodium salt form and appears as a white, powdery solid at room temperature and pressure. This compound is soluble in water and insoluble in ethanol, facilitating easy concentration adjustments via its sodium salt.
Known for its antimicrobial efficacy against various bacteria such as black mold and Staphylococcus aureus, dehydroacetic acid exhibits bacteriostatic properties against molds, yeasts, and gram-positive bacteria within an acidic range. It is incorporated as a pharmaceutical additive for base, disintegration, antiseptic, preservation, and dissolution in oral, topical, ophthalmic, and otolaryngological formulations.
Due to its minimal irritation potential and antimicrobial activity, dehydroacetic acid is also used as a preservative in cosmetics, including makeup, skincare, and hair care products. The inclusion of dehydroacetic acid in cosmetic formulations is capped at 0.5g per 100g to ensure safety.
As a food additive, it enhances the preservative qualities of fermented foods like butter, cheese, and margarine. While approved by the Ministry of Health, Labour and Welfare, and the EU, its actual use in Japan is infrequent; however, it is specified that residual amounts in EU products should not exceed 500 mg per kg. It is also utilized in dog food preservatives, with the advisory to check ingredient labels for potential concerns.
Dehydroacetic acid is characterized as a white crystalline powder, with a molecular weight of 208.14 and assigned CAS number 64039-28-7. Absent data on its melting point, flash point, or flammability, it remains stable under typical conditions but may degrade upon light exposure. Precautions should be taken to avoid high temperatures, direct sunlight, and reactive oxidizing agents, as it may decompose into hazardous gases like carbon monoxide and dioxide.
Classified with class 4 acute toxicity (oral) by the GHS, it is harmful if ingested. Immediate actions include rinsing the mouth and contacting a poison center or physician. It is essential to wash thoroughly after handling to remove potential residues.
In cases of inhalation, seek fresh air promptly. If contact occurs with skin or eyes, wash the area with soap and water or rinse the eyes for several minutes, respectively. Medical attention should be sought if symptoms persist.
Ensure work areas are well-ventilated and equipped with safety showers and eyewash stations. Protective gear such as dust-proof masks, gloves, and goggles should be worn during handling to prevent exposure.
Dehydroacetic acid should be stored in a cool, well-ventilated place away from light and strong oxidizers. Suitable containers include those made from polypropylene and polyethylene, and disposal should comply with national or local regulations.
*Including some distributors, etc.
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ChemScence, LLC., established in 2006, is an American manufacturer based in Monmouth Junction, New Jersey, specializing in building blocks and fine research chemicals. The company offers approximately 45,000 building blocks and intermediates, as well as thin layer chromatography, screening libraries, bioactive small molecules, and isotope compounds. ChemScence also provides dye and biochemical assay reagents, peptides, and natural products like glycosides, and steroids. Catering to a diverse clientele including universities, research institutions, as well as pharmaceutical and biotechnology companies, ChemScence extends its services to include custom chemistry solutions. Furthermore, the company offers technical expertise in the domain of new drug development.
United States Biological, located in Salem, Massachusetts, is a manufacturer and supplier of life science research products. Its product offerings include biochemicals, antibodies, and molecular biology kits. The company’s products are used in various fields such as genomic research, biotechnology, and pharmaceutical development. Products are available from affordable research quantities to larger bulk amounts for process development and production. Its customer base comprises pharmaceutical and biotechnology companies both in the US and overseas.
Neuchem is a distributor of specialty chemicals and raw materials, founded in 1993, and headquartered in Sparks, Nevada, USA. Its product offerings include acids, alcohols, amines, esters, as well as glycols, and solvents. These products are used for various industrial applications such as coatings, adhesives, plastics, rubber, cosmetics, and pharmaceuticals. The company assumes material ownership at the foreign port, manages ocean freight, customs clearance, terminal storage, and final delivery across the USA and Canada, as well as handle packaging, order documents, shipment updates, and coordinate until final delivery.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Cowin Industry Limited Shandong Hirch Chemical Co., Ltd. was founded in 1993 and is headquartered in Shandong, China, as a manufacturer and exporter of oil drilling chemicals in china. The company offers a wide range of quality products, including Soda Ash, Silica Gel, Bromine Tablets, White Silica Gel, Blue Silica Gel, Orange Silica Gel, Sodium Silicate, Calcium Chloride, Sodium Pyrosulfite, and various other items. The company has been providing clients with worth in the form of chemical products at a competitive pricing structure. The organization maintains a substantial inventory of merchandise to meet the immediate needs of esteemed customers.
Avantor was founded in 1904 and is headquartered in Radnor, Pennsylvania, as a supplier of lab and production services such as general and technical lab services, production, and business process consulting services. The company offers various clinical services, including customized kitting solutions, clinical trial equipment, and ancillary services. The organization is regarded as a dependable global partner for customers and suppliers in the life sciences, advanced technologies, and applied materials industries, spanning from initial discovery to final delivery.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Ataman Kimya, established in 2006, is a distributor of chemicals based in Istanbul, Turkey. Their wide range of products includes detergents, cosmetics, disinfectants, pharmaceutical chemicals, and water treatment chemicals. They also offer textile, leather, paper, and mining chemicals. These chemicals, such as hydrogenated castor oils, ethanol, and butylene glycol, find applications in various industries, such as personal care, household cleaning, fragrance, coatings, and agriculture. The company also offers custom blending to meet specific requirements.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | ChemScence |
37.5%
|
2 | ATAMAN Kimya A.S. INC. |
25.0%
|
3 | Neuchem |
12.5%
|
4 | Junsei Chemical Co.,Ltd. |
12.5%
|
5 | KANTO CHEMICAL CO.,INC. |
12.5%
|
Derivation Method
The ranking is calculated based on the click share within the dehydroacetic acid page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 4 | 44.4% |
Japan | 3 | 33.3% |
China | 1 | 11.1% |
India | 1 | 11.1% |