10 Thiamine Disulfide Manufacturers in 2024
This section provides an overview for thiamine disulfide as well as their applications and principles. Also, please take a look at the list of 10 thiamine disulfide manufacturers and their company rankings. Here are the top-ranked thiamine disulfide companies as of November, 2024: 1.CYMIT QUÍMICA S.L., 2.AK Scientific, Inc, 3.Biosynth.
Table of Contents
What Is Thiamine Disulfide?
Thiamine disulfide, a derivative of vitamin B1, serves as an essential nutrient, aiding in the treatment of thiamine deficiency and related health conditions with its superior absorption and efficacy.
Uses of Thiamine Disulfide
Employed in preventing and treating thiamine deficiencies, thiamine disulfide has historical significance in combating beriberi and is currently utilized in addressing conditions like Wernicke's encephalitis and pre-diabetes.
Properties of Thiamine Disulfide
Thiamine disulfide, a white or light yellow solid, decomposes at 179°C, showcasing solubility in dilute acids but limited solubility in water and organic solvents.
Structure of Thiamine Disulfide
As a thiamine derivative, thiamine disulfide features a disulfide bond between sulfur atoms, obtained through the alkaline iodine oxidation of thiamine.
Other Information on Thiamine Disulfide
1. Effects
Crucial for energy conversion and nerve function, thiamine disulfide supplementation aids in treating neuralgia and muscle pain, highlighting the importance of vitamin B1 intake.
2. Mechanism of Action
Thiamine disulfide, upon reduction, plays a pivotal role in carbohydrate, protein, and lipid metabolism by participating in crucial biochemical cycles.
3. Metabolism
Being water-soluble, thiamine disulfide is excreted through urine, with typical adult dosages ranging from 1 to 10 mg orally 1 to 3 times a day.
4. Other Vitamin B1 Derivatives
Various vitamin B1 derivatives, including octothiamine and benfotiamine, are utilized in medicine and as food additives, expanding the scope of thiamine's application.
List of 10 Thiamine Disulfide Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Canada
- India
- Japan
- Spain
- Switzerland
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MedChemExpress
Thiamine disulfide
Manufacturer Overview
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
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AK Scientific, Inc
Thiamine disulfide, >98% (HPLC)
Manufacturer Overview
AK Scientific, Inc. (AKS) is an American advanced intermediates and fine chemicals manufacturer that was established in Union City, California in 1997. The company’s product lineup includes chemical biocides, bioactives, inhibitors, and reagents. It also offers a range of products for use in life science applications, such as screening compounds, organoborons, and molecular fluorophores. These are extensively used in agrochemicals, biotech, pharmaceuticals, and nanotechnology. Aside from its products, AKS also offers international procurement and sourcing services to its clients, which include AstraZeneca, Sanofi-Aventis, and Bristol-Myers Squibb.
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Santa Cruz Biotechnology, Inc.
Thiamine Disulfide
Company Overview
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
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SIELC Technologies
Thiamine disulfide
Company Overview
SIELC Technologies is a specialized manufacturer and developer of high-performance liquid chromatography (HPLC) columns, devices, and systems. The company was founded in 2001 and is based in Illinois, with a network of partner distributors in over 30 countries across six continents. The company's product portfolio is centered around various HPLC columns including chiral, normal- and reverse-phase, ion-exchange, and mixed-mode models. These supply clients in the biotech, pharmaceutical, petrochemical, and cannabis industries.
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SimSon Pharma Limited
Dibenzoyl Thiamine
Manufacturer Overview
SimSon Pharma Limited, established in 2011 and headquartered in Mumbai, India, is a manufacturer and supplier of pharmaceutical reference materials. Their product range includes drug working standards, drug impurity standards, drug metabolites, and stable isotope labeled compounds. These provide a basis for comparison and validation, enabling pharmaceutical companies to produce safe and effective medications. The company's offerings serve specific purposes, such as calibrating analytical instruments and ensuring precise analytical results, identifying and quantifying impurities in drugs, understanding drug metabolism, and developing new drug therapies.
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Biosynth
Thiamine disulfide
Manufacturer Overview
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
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Tokyo Chemical Industry Co., Ltd.
Thiamine Disulfide
Manufacturer Overview
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
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Toronto Research Chemicals
Thiamine Disulfide Hydrate
Manufacturer Overview
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
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MilliporeSigma
Thiamine Disulfide
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Thiamine Disulfide Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | CYMIT QUÍMICA S.L. |
30.0%
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| 2 | AK Scientific, Inc |
15.0%
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| 3 | Biosynth |
15.0%
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| 4 | MilliporeSigma |
15.0%
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| 5 | SimSon Pharma Limited |
10.0%
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| 6 | SIELC Technologies |
5.0%
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| 7 | Tokyo Chemical Industry Co., Ltd. |
5.0%
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| 8 | MedChemExpress |
5.0%
|
Derivation Method
The ranking is calculated based on the click share within the thiamine disulfide page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
- SIELC Technologies: 2002 (22 years ago)
- CYMIT QUÍMICA S.L.: 2000 (24 years ago)
- Toronto Research Chemicals: 1982 (42 years ago)
Company with a History
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
- Biosynth: 1966 (58 years ago)
- Toronto Research Chemicals: 1982 (42 years ago)
Thiamine Disulfide Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Thiamine Disulfide Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
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4 | 44.4% |
India
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1 | 11.1% |
Switzerland
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1 | 11.1% |
Japan
|
1 | 11.1% |
Canada
|
1 | 11.1% |
Spain
|
1 | 11.1% |
