All Categories
History
This section provides an overview for spiramycin as well as their applications and principles. Also, please take a look at the list of 10 spiramycin manufacturers and their company rankings. Here are the top-ranked spiramycin companies as of December, 2024: 1.Rooyan Darou, 2.Biomol GmbH, 3.GoldBio.
Table of Contents
Spiramycin is a macrolide antibiotic with the chemical formula C43H74N2O14, recognized for its application in preventing congenital toxoplasmosis in fetuses when administered to pregnant women infected with toxoplasma. Discovered in 1954 from a soil actinomycete in France, spiramycin's effectiveness against toxoplasmosis led to its approval in Japan in 2018.
Spiramycin is primarily used to prevent congenital toxoplasmosis, an infection that poses severe risks to fetuses, including stillbirth, miscarriage, and developmental disorders. It operates as a bacteriostatic agent, inhibiting bacterial growth by preventing protein synthesis within bacterial cells.
By binding to the 50S subunit of bacterial ribosomes, spiramycin halts protein biosynthesis, acting as a bacteriostatic rather than bactericidal agent. It is metabolized to neospiramycin in the stomach and is excreted primarily via bile. During pregnancy, it can cross the placenta, reaching the fetus. Common side effects include gastrointestinal issues, allergic reactions, and liver dysfunction.
Spiramycin features a 16-membered macrolide ring, characteristic of macrolide antibiotics, which includes three sugar structures that enhance its water solubility, stability, and antibacterial activity.
Produced via fermentation using Streptomyces ambofaciens, spiramycin is extracted from cultures of this actinomycete. Its complex structure necessitates biological synthesis, followed by purification through chromatography and recrystallization.
*Including some distributors, etc.
Sort by Features
Sort by Area
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
GoldBio, founded in the United States in 1986, is a supplier of quality lab products for research and molecular biology. The company offers a range of lab consumables, including pipettes, tubes, plates, and more, to support precise and efficient molecular biology research and a wide array of reagents and kits for applications in genomics, proteomics, cell biology, and other critical areas of study. Its products are used for clinical diagnostics to ensure accurate and reliable test results for healthcare providers.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Biomol GmbH, founded in 1968 and headquartered in Heidelberg, Germany, is a manufacturer, supplier, and distributor of life science products for the biomedical research domain. The company's range of products includes primary antibodies that originate from different host species such as mouse, rabbit or goat, dyes and labeling reagents, qPCR gene family primers, as well as virus-based tools used to manipulate genetic material and study viral infections. These scientific resources find applications across various disciplines, including molecular biology, academic research of drug development, pharmaceutical development of antibodies, and clinical diagnostics of viral infections.
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Rooyan Darou |
31.3%
|
| 2 | GoldBio |
12.5%
|
| 3 | Biomol GmbH |
12.5%
|
| 4 | MilliporeSigma |
12.5%
|
| 5 | Cayman Chemical Company |
6.3%
|
| 6 | Glentham Life Sciences Limited |
6.3%
|
| 7 | Alfa Aesar, Thermo Fisher Scientific. |
6.3%
|
| 8 | Santa Cruz Biotechnology, Inc. |
6.3%
|
| 9 | KANTO CHEMICAL CO.,INC. |
6.3%
|
Derivation Method
The ranking is calculated based on the click share within the spiramycin page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 44.4% |
|
United Kingdom
|
2 | 22.2% |
|
Japan
|
1 | 11.1% |
|
Germany
|
1 | 11.1% |
| Iran | 1 | 11.1% |
