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This section provides an overview for distigmine as well as their applications and principles. Also, please take a look at the list of 8 distigmine manufacturers and their company rankings. Here are the top-ranked distigmine companies as of December, 2024: 1.GNH India.
Table of Contents
Distigmine, also known as distigmine bromide, is a chemical compound with the formula C22H32Br2N4O4.
Distigmine functions by inhibiting cholinesterase, an enzyme that breaks down acetylcholine—a key neurotransmitter in parasympathetic and motor nerves. By inhibiting cholinesterase, distigmine helps maintain higher levels of acetylcholine.
Distigmine is utilized in medical treatments due to its cholinesterase-inhibitory properties.
It plays a crucial role in enhancing muscle contraction, particularly beneficial in conditions like hypotonic bladder.
Additionally, distigmine is effective in treating myasthenia gravis, an autoimmune disorder that weakens muscles. It increases acetylcholine levels, thereby improving nerve-muscle signal transmission.
*Including some distributors, etc.
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MedKoo Biosciences, Inc. is an American manufacturer of biochemical reagents established in 2009 and based in Morrisville, North Carolina. Specializing in small molecule drugs for laboratory use, the company offers a wide range of products including apoptosis inducers, anticancer reagents, epigenetic modulators, and various pharmaceutical related chemicals. These have applications in various fields including microbiology, stem cell research, endocrinology, and epigenetics. MedKoo Biosciences also provides R&D services to client biotechnology, biomedical, and pharmaceutical companies, as well as academic institutions.
ChemScence, LLC., established in 2006, is an American manufacturer based in Monmouth Junction, New Jersey, specializing in building blocks and fine research chemicals. The company offers approximately 45,000 building blocks and intermediates, as well as thin layer chromatography, screening libraries, bioactive small molecules, and isotope compounds. ChemScence also provides dye and biochemical assay reagents, peptides, and natural products like glycosides, and steroids. Catering to a diverse clientele including universities, research institutions, as well as pharmaceutical and biotechnology companies, ChemScence extends its services to include custom chemistry solutions. Furthermore, the company offers technical expertise in the domain of new drug development.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
GNH India, based in Mumbai, India, is a distributor of pharmaceutical products. The company caters to the whole spectrum of pharmaceutical trade starting from wholesale, tender supplies, orphan drugs, name patient access, biologics and vaccines. It sources from over 60 countries offering over 2,03,000 product lines covering original brands and true generic. It also provides contract manufacturing services for generic medicines and validated cold chain shipment services. The company has certified quality management and has acquired several certifications including ISO 9001:2015 for risk management criteria and WHO GSDP for preserved quality of pharmaceutical products and good distributive practices.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | GNH India |
100.0%
|
Derivation Method
The ranking is calculated based on the click share within the distigmine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
2 | 40.0% |
|
Canada
|
2 | 40.0% |
|
Switzerland
|
1 | 20.0% |
