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This section provides an overview for oryzanol as well as their applications and principles. Also, please take a look at the list of 6 oryzanol manufacturers and their company rankings. Here are the top-ranked oryzanol companies as of December, 2024: 1.Alfa Chemistry, 2.NutriScience Innovations, LLC, 3.Santa Cruz Biotechnology, Inc..
Table of Contents
Oryzanol is a collection of compounds consisting of phytosterols or triterpene alcohols bound to ferulic acid.
Oryzanol is known to possess a variety of properties in addition to its antioxidant capacity. Among oryzanols, gamma oryzanol is the most well-known and most commonly used.
Gamma-oryzanol is abundant in rice in nature. It is found naturally in rice, especially in brown rice (especially rice bran). It is expected to reduce cholesterol in the body and support the autonomic nervous system.
Gamma oryzanol is a stable substance that does not decompose easily, even at high temperatures, and is safe for the human body.
The main use of oryzanol is for application to the human body. Gamma oryzanol, the most commonly used oryzanol, has various properties for the human body.
These properties are mainly used in pharmaceuticals, cosmetics, and foods. The daily oral dosage for pharmaceuticals has a range from 10 mg to 50 mg. The maximum amount that can be added to cosmetics and foods is also determined.
In the pharmaceutical field, it is used in the treatment of psychosomatic disorders such as menopausal disorders and irritable bowel syndrome, and in the treatment of hyperlipidemia. In the treatment of psychosomatic disorders, it is expected to increase the amount of noradrenaline, a neurotransmitter in the brain, and to move the digestive organs.
Thus, anxiety, depression, and digestive symptoms are likely to improve. In the treatment of hyperlipidemia, it is expected to improve dyslipidemia by reducing the absorption of cholesterol, etc.
In the field of cosmetics, two main effects can be expected: first, protection against ultraviolet rays. There are two main types of ultraviolet rays: UVA, which has a longer wavelength, and UVB, which has a shorter wavelength.
γ-oryzanol absorbs mainly UVB rays. γ-oryzanol is oil-soluble, so it is used in cosmetics such as milks and creams that contain many oil-based ingredients.
Another effect in the field of cosmetics is its antioxidant effect, i.e., its ability to protect the skin by removing active oxygen, which can also be a cause of skin aging. Antioxidant is the action of preventing oxidation.
Oxidation can be easily understood as rusting, and when oxidation occurs in the skin due to the effects of ultraviolet rays, it can cause wrinkles and other skin problems. It is thought that the presence of γ-oryzanol, which has an antioxidant effect, in the skin can inhibit oxidation that causes wrinkles.
In the field of food, it is approved to be added as a food additive. It can be added as an antioxidant. In addition, supplements containing γ-oryzanol are commercially available. γ-oryzanol is also used as an ingredient in health foods.
The main characteristic of γ-oryzanol is it is oil soluble, meaning that it does not dissolve in water. Since γ-oryzanol is mainly contained in rice bran, rice oil derived from rice bran also contains γ-oryzanol.
γ-oryzanol has more than one molecular structure. As mentioned above, γ-oryzanol is an ester compound of ferulic acid and phytosterol or triterpene alcohol.
However, due to the various structures of phytosterols or triterpene alcohols, there are many types of γ-oryzanol.
γ-oryzanol was first extracted from rice by Japanese researchers in 1953. The scientific name for rice is Oryza sativa, which is the origin of the substance name oryzanol.
Although oryzanol, especially γ-oryzanol, is found in high concentrations specifically in rice bran, oryzanol is also found in other plants. For example, oryzanol is also present in wheat, corn, or millet. Trace amounts of oryzanol are also present in kelp.
*Including some distributors, etc.
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Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Alfa Chemistry, founded in the year 2015 is based in New York, USA as a biotechnology company and manufacturer of graphene materials. Their product portfolio includes graphene oxide, CVD graphene film, graphene modification services, graphene series, graphene-like material, carbon nanomaterials, quantum dots, upcoming nanoparticles, and graphene transfer services. The company also provides services in custom manufacturing, and graphene analysis with quality assurance. The products are used in various industries which include energy, digital electronics, environment, textile, coating, and biomedical science.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Fengchen Group Co., LTD is based in Qingdao, China. The company is a manufacturer and supplier of speciality chemicals for several industries around the world including natural resources, hydrogeology, drilling, geophysics, and environmental & geotechnical services. The company’s chemical product categories include APIs, amino acids, micronutrients, package materials, and enzymes. The company also offers services including specialized transportation, samples of compounds, shipping documents needed for pharmaceutical products, and international customs support.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Alfa Chemistry |
25.0%
|
| 2 | Santa Cruz Biotechnology, Inc. |
21.7%
|
| 3 | NutriScience Innovations, LLC |
20.0%
|
| 4 | Ricela Group of Companies |
15.0%
|
| 5 | MilliporeSigma |
13.3%
|
| 6 | Fengchen Group Co.,Ltd |
5.0%
|
Derivation Method
The ranking is calculated based on the click share within the oryzanol page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
2 | 50.0% |
| United States | 1 | 25.0% |
India
|
1 | 25.0% |
