All Categories
History
This section provides an overview for pitocin as well as their applications and principles. Also, please take a look at the list of 11 pitocin manufacturers and their company rankings. Here are the top-ranked pitocin companies as of December, 2024: 1.AdvaCare Pharma USA, 2.Pfizer, 3.Par Pharmaceutical.
Table of Contents
Pitocin is an organic compound with the molecular formula C43H66N12O12S2, and is a peptide hormone.
It is synthesized in the neurosecretory cells of the para ventricular nucleus and suprachiasmatic nucleus of the hypothalamus and secreted from the pituitary gland.
Pitocin is closely related to oxytocin in women, where it is well known as a hormone that stimulates the secretion of prostaglandins, which also causes menstrual cramps and induces labor pains. Recently, it has also been found to be secreted by kinship with people and animals, and is now also known by the aliases "affection hormone" and "happy hormone."
Pitocin is a hormone that is generally synthesized and secreted by the body. Therefore, it is often used to affect people rather than objects.
In the early 20th century, it was known to accelerate labor and induce the ejaculation reflex during postpartum lactation, hence its name from the Greek okytokos (early (okys), which is also the origin of the name okytokos (early (okys) birth (tokos)). Thus, it is a familiar substance in obstetrics and gynecology, as it is often used to act in the uterine area.
Other uses include weak labor, flaccid hemorrhage, before and after placental delivery, inadequate uterine restoration, cesarean section after delivery of a fetus, miscarriage, and abortion.
Pitocin is a white powder that is extremely soluble in water and readily soluble in ethanol (99.5) and hydrochloric acid reagent.
It acts as a hormone in peripheral tissues and as a neurotransmitter in the central nervous system. In the peripheral tissues, it is mainly involved in the contraction of smooth muscle, which causes uterine contraction during childbirth. Oxytocin also contracts the muscle fibers of the mammary gland to stimulate milk secretion.
The structure of Pitocin is a large ring composed of two cysteines: tyrosine, isoleucine, glutamine, and asparagine, and the sulfur atoms of the two cysteines in the ring are connected by disulfide bonds. There are three amino acids (proline, leucine, and glycine) that also branch off from one cysteine. Vasopressin, another posterior pituitary hormone, is similar in structure to pitocin, differing only in two amino acids.
Pitocin was discovered by Henry Hallett Dale in 1906, and its molecular structure was determined in 1952. The Nobel Prize in Chemistry was awarded in 1955 to Vincent du Vigneault and his colleagues, who were the first to biosynthesize it and determine its structure successfully.
There are two main types of pitocin products on the market today: clinical drugs and reagents for research and development. Clinical drugs are marketed primarily as injectable atonin and are used primarily during labor and delivery.
Intranasal pitocin is approved in Europe for the promotion of lactation. Its efficacy in improving sociability in autism spectrum disorders is also being tested by national and international researchers.
Test kits for detecting pitocin are commercially available and can measure oxytocin in culture supernatants, milk, serum, and plasma. Its use in cerebrospinal fluid, saliva, tissue, and urine samples has also been reported in a number of studies.
Precautions for handling and storage are as follows:
*Including some distributors, etc.
Sort by Features
Sort by Area
AdvaCare Pharma USA LLC, founded in 2014, is an American pharmaceutical manufacturer and supplier based in Cheyenne, Wyoming. The company specializes in a wide range of products, including over-the-counter (OTC) medicines, supplements, antimalarial tablets, injections, and oral suspensions. They also offer oncology tablets, injections, and powder for injections, as well as veterinary products and medical devices like injection instruments, diagnostic detection instruments, and skin and wound care products. AdvaCare's products are available under various brands, such as AmoxiCare™ for amoxicillin capsules and AdvaLife™ for supplements.
Pfizer Inc., an American multinational pharmaceutical and biotechnology manufacturing corporation, was established in 1849 in New York. The company is a major manufacturer of biopharmaceuticals, offering products to treat different conditions such as cardiovascular, metabolic and pain, women’s health, cancer, immune disorders, and rare diseases. It applies science and global resources to bring therapies to people that extend and significantly improve their lives. Its portfolio includes medicines and vaccines, as well as many of the world’s famous consumer health care products. It works across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases.
Pace Biotech, established in 2010 and headquartered in Himachal Pradesh, India, is a pharmaceutical manufacturer specializing in pharmaceutical injections, ear drops, and eye drops. The company's product portfolio includes a range of offerings such as dry injections, dry powder non-beta lactum block, hormonal injections, ophthalmic drops, and various other ophthalmic products. The company serves various segments of the life science industry, including biotech, clinical research, and pharmaceutical sectors. It is one of the WHO GMP injection manufacturers in India.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Lexicare Pharma Pvt. Ltd., established in 2005 in Gujarat, India, is a manufacturer and supplier of pharmaceutical, ayurvedic, veterinary, and nutraceutical solutions, which are categorized into gummies, effervescent tablets, anti-venom serum, anti-cancer medicine, and hormone products. The company's product catalog includes Ginseng softgel capsules, antisnake venom serum, Alpha lipoic acid softgel capsules, growth hormones, and I.V. fluids. It has partnered with freight forwarding agencies that help distribute the products to over 15 countries.
Pharma Cure Laboratories, established in 1987 and headquartered in Jalandhar, India, operates as a manufacturer and supplier of pharmaceutical and veterinary products, including injections, tinctures, and anabolic steroids. The company's product portfolio includes a range of offerings, such as sodium bicarbonate injection, tranexamic acid injection, hyoscine butylbromide injection, folic acid and niacinamide injection, vitamin B12 injection, and more. The company serves various sectors in the life science industry, including biotech, clinical research, and pharmaceutical enterprises.
Taj Pharmaceuticals Limited, established in 1995 and headquartered in Mumbai, India, is a global manufacturer and supplier of generic medicines, healthcare, and other products. The company markets more than 500 branded and 4600 generic compositions to consumers in over 40 countries and territories across the globe. Its products cover a vast array of therapeutic categories, and offers an extensive range of dosage forms and delivery systems including oral solids, controlled-release, and steriles. Some of its offerings are diabetic care products, insulin, and growth hormones. The company holds the ISO 9001:2000 certification for its quality management system.
McKesson Medical-Surgical, located in the United States, is a distributor of medical supplies established in 1833. The company offers healthcare solutions, clinical resources, and distribution services. They provide a wide range of medical products with the largest delivery vehicle fleet and over 900 delivery professionals nationwide. In addition to their distribution services, they provide laboratory and pharmaceutical services, as well as solutions for inventory management. Their technology consultants offer a no-cost evaluation of the customers' supply and inventory workflow, providing with recommendations on how to drive savings and efficiencies to help uncover opportunities and match solutions to customers' specific needs.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | AdvaCare Pharma USA |
31.6%
|
| 2 | Pfizer |
26.3%
|
| 3 | Par Pharmaceutical |
13.2%
|
| 4 | MilliporeSigma |
7.9%
|
| 5 | Lexicare Pharma Pvt. Ltd. |
5.3%
|
| 6 | Pace Biotech |
5.3%
|
| 7 | Taj Pharmaceuticals Limited |
5.3%
|
| 8 | McKesson Medical-Surgical Inc. |
2.6%
|
| 9 | nacalai |
2.6%
|
Derivation Method
The ranking is calculated based on the click share within the pitocin page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
5 | 62.5% |
|
United States of America
|
2 | 25.0% |
|
Japan
|
1 | 12.5% |
