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This section provides an overview for terramycin as well as their applications and principles. Also, please take a look at the list of 9 terramycin manufacturers and their company rankings. Here are the top-ranked terramycin companies as of December, 2024: 1.HILLSIDE VETERINARY SURGERY, 2.Zoetis Services LLC, 3.Phibro Animal Health Corporation.
Table of Contents
Terramycin, also known as oxytetracycline, is a broad-spectrum antibiotic isolated from the actinomycete Streptomyces rimosus. It belongs to the tetracycline antibiotics class and binds to the 30S ribosomal subunit of bacteria to inhibit protein synthesis, exhibiting bacteriostatic activity.
Terramycin is used in human medicine to treat various bacterial infections, including acne, chlamydia infections, mycoplasma infections, Haemophilus influenza, and rickettsial infections. It is also widely used in veterinary medicine and as a pesticide against bacterial diseases of crops.
The chemical formula of Terramycin is C22H24N2O9, with a molecular weight of 460.434 g/mol. It is a yellow crystal, soluble in water and slightly soluble in ethanol. The in vivo half-life is 6-8 hours.
Terramycin has a broad antibacterial spectrum, effective against gram-positive and gram-negative bacteria, Chlamydia, and Mycoplasma, although some bacteria may develop resistance.
Topical application may cause itching and swelling. Internal use can lead to gastrointestinal symptoms, photosensitivity, and, rarely, damage to high-calcium organs like teeth and bones.
Similar natural tetracycline antibiotics include tetracycline and chlortetracycline. Chlortetracycline differs from tetracycline by the substitution of a chlorine atom.
Terramycin is prescribed for 6-8 weeks for moderate to severe acne, but alternative treatments should be considered if there is no improvement after 3 months. It is also effective against clostridial and spirochete infections and can be used for patients allergic to penicillins or macrolides. Doxycycline, with improved pharmacological properties, is often chosen for treating various infections.
*Including some distributors, etc.
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Phibro Animal Health Corporation is a manufacturer of products and solutions for the animal agriculture industry, headquartered in New Jersey, USA, dating back to 1947. The company offers diverse products and services, including animal health products, mineral nutrition, feed ingredients, nutritional specialty products, and contract manufacturing. The company's solutions are utilized in various segments of the animal agriculture industry, including dairy, poultry, swine, cattle, and aquaculture, working with producers, veterinarians, and nutritionists to improve animal well-being and production efficiency. The company operates globally, serving customers in numerous countries worldwide.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Syndel Canada, established in 1983, is a manufacturer and distributor of fish health products for the aquaculture industry, located in British Columbia, Canada. The company offers a range of products including anesthetics, disinfectants, and vaccines for fish. These products are utilized in fish reproduction, disease prevention, disease treatment, and biosecurity measures aimed at enhancing the overall health of fish and preventing the spread of diseases. Syndel Canada holds certifications from the Canadian Food Inspection Agency (CFIA) and the United States Department of Agriculture (USDA).
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | HILLSIDE VETERINARY SURGERY |
43.9%
|
| 2 | Zoetis Services LLC |
17.1%
|
| 3 | Phibro Animal Health Corporation |
17.1%
|
| 4 | nacalai |
7.3%
|
| 5 | Alinamin Pharmaceutical Co.,Ltd. |
4.9%
|
| 6 | MilliporeSigma |
4.9%
|
| 7 | Santa Cruz Biotechnology, Inc. |
2.4%
|
| 8 | KANTO CHEMICAL CO.,INC. |
2.4%
|
Derivation Method
The ranking is calculated based on the click share within the terramycin page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
3 | 42.9% |
|
Japan
|
3 | 42.9% |
Singapore
|
1 | 14.3% |
