This section provides an overview for ethylene glycol dibutyl ethers as well as their applications and principles. Also, please take a look at the list of 12 ethylene glycol dibutyl ether manufacturers and their company rankings. Here are the top-ranked ethylene glycol dibutyl ether companies as of November, 2024: 1.MilliporeSigma.
Table of Contents
Ethylene glycol dibutyl ether is a compound with two ether groups.
It is also known by various other names, such as "ethylene glycol di-n-butyl ether," "1,2-dibutoxyethane," and "5,8-dioxadodecane."
At room temperature, it is a colorless, to slightly pale-yellow liquid that is insoluble in water. It is flammable and should be kept away from heat, hot bodies, and fire.
Ethylene glycol dibutyl ether is used in the composition of a material called "photoresist." Photoresist is a material used in semiconductor etching (a surface processing technique that uses the corrosive action of chemicals).
In the processing of semiconductor components, etching is used to form minute grooves for printing circuits and other components. What is important in etching is that only the areas to be etched are exposed to the chemical, while the areas not to be etched are coated with a corrosion-resistant photoresist.
In order to control the shape of the coated area precisely, a photoresist is applied to the semiconductor surface and then irradiated with light or electron beams of specific wavelengths to bake a pattern of the shape to be coated. After that, a developing solution is used to dissolve and remove the unneeded photoresist, and the areas without photoresist are etched.
This process selectively corrodes portions of semiconductors, making it possible to create integrated circuits with complex structures.
Ethylene glycol dibutyl ether is represented by the molecular formula C10H22O2 . The structure is an ether bond of one molecule of ethylene glycol (C2H6O2), a divalent alcohol, and two molecules of butanol (C4H10O).
The basic properties (molecular weight, specific gravity, and solubility) of ethylene glycol dibutyl ether are as follows:
Ethylene glycol is a divalent alcohol with two hydroxy groups in its molecule. Each of these hydroxy groups forms an ether bond, so that dehydration condensation with two molecules of butanol yields ethylene glycol dibutyl ether.
Because oxygen atoms are highly electronegative, the ether bond is polarized. However, the ethylene glycol dibutyl ether molecule has a point-symmetric linear structure, so the molecule as a whole has low polarity.
Ethylene glycol dibutyl ether is a flammable liquid. Since its flash point is 85°C, flammable vapor may be generated when used in exothermic reactions or in heating experiments.
Vapor density is higher than that of air, and if leaked indoors, it may be retained on the floor, so it is preferable to handle it in a draft with ventilation. In case of fire, use powder extinguisher, foam extinguisher, or carbon dioxide extinguisher. Since they are insoluble in water, bar pouring may cause the spread of fire and is very dangerous.
Ethers can form explosive oxides (peroxides) when oxidized by contact with oxygen or exposure to ultraviolet light. Accumulation of explosive oxides may cause an explosion upon heating or impact.
To prevent the accumulation of oxides, it is effective to add antioxidants (hydroquinone, etc.), seal with nitrogen, or shield from ultraviolet rays. When using ethylene glycol dibutyl ether that has been stored for a long time, it is safer to check for the accumulation of oxides with a test paper.
Ethylene glycol dibutyl ether is irritating to the skin and eyes. When handling, protective equipment such as protective gloves and safety glasses should be worn, and drafts or local exhaust ventilation should be operated to avoid exposure to vapors. If it adheres to the skin, it must be washed immediately.
Acute toxicity is also present, and the half lethal dose (LD50 value) in rats is 2,650 mg/kg administered orally. The substance name must be clearly indicated on the label, and the product must be stored and used in a well-ventilated area.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Greyhound Chromatography and Allied Chemicals Ltd has been a manufacturer, supplier, and distributor of chromatography consumables to research and analysis laboratories since 1981. The company offers chromatography columns, consumables, certified reference standards and materials, research chemicals, and solvents. It also provides reagents and laboratory consumables. The company serves a broad spectrum of industries, including environmental, petrochemical, food, chemical, and pharmaceutical analysis. The company holds certifications like ISO 9001:2015 for its quality management system.
Shanghai Theorem Chemical Technology Co., Ltd., established in 1997, is a company located in Shanghai, China, is a manufacturing company specializing in researching and manufacturing chemical new materials and fine chemicals. The company offers new functional materials, surfactants, polyurethane chemicals, special isocyanates, extractants, and more. They have a product chain advantage and offer professional technical support, and stable production supply with authorized ISO9001 quality management system, ISO14001 environmental management system, as well as related certifications. Their manufacturing factory with a land area of 80,000 m2, has over 300 workers, 30 engineers, 7 production workshops.
CHEMOS GmbH & Co. KG is a supplier of ready-to-use solutions for the lab and chemical sector. It is headquartered in Altdorf, Germany, and was established in 1974. The company supplies a range of reagents and standards for the analytical lab, as well as raw materials for the chemical and pharmaceutical sector. Some of its popular products are volumetrical reagents, standards and references, and products for research. CHEMOS also provides services such as drying, grinding and sieving, recrystallization and purification as well as contract manufacturing and contract synthesis. Its products are used in various industries, including pharmaceuticals, food, and environmental testing.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | MilliporeSigma |
100.0%
|
Derivation Method
The ranking is calculated based on the click share within the ethylene glycol dibutyl ether page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 3 | 27.3% |
China | 3 | 27.3% |
United States of America | 2 | 18.2% |
Switzerland | 1 | 9.1% |
United Kingdom | 1 | 9.1% |
Germany | 1 | 9.1% |