This section provides an overview for inositol as well as their applications and principles. Also, please take a look at the list of 14 inositol manufacturers and their company rankings. Here are the top-ranked inositol companies as of November, 2024: 1.SAE Manufacturing Specialties Corp, 2.Standard Process Inc., 3.NOW Foods.
Table of Contents
Inositol (chemical formula: C6H12O6) is a sugar alcohol biosynthesized from glucose. It is one of the bioactive substances deeply involved in cell proliferation and canceration, and is abundant in muscle and nerve cells.
Inositol is known as a vitamin-like substance and is a component of cell membranes. It exists in crystalline form at room temperature.
There are a total of nine stereoisomers, and myoinositol is usually referred to as inositol. This is because only myoinositol has biological activity and has been widely studied.
Inositol is widely used in the production of pharmaceuticals, cosmetics, and food additives.
Inositol is used as a liver function improver and as an antidepressant. It is also involved in calcium and lipid metabolism in the body and is used in the prevention and treatment of diabetes because of its effect on lowering blood sugar levels.
In addition, it is expected to improve polycystic ovary syndrome and panic disorder, and is being studied.
Inositol binds to phosphoric acid in the body and acts on blood cholesterol and the nervous system of the brain. It has an effect of facilitating the elimination of fat, and is expected to prevent and improve lifestyle-related diseases.
In addition, inositol is often used as an additive in food supplements and foods to maintain normal nerve function and healthy hair.
Inositol is a white crystalline powder with a molecular weight of 180.16 g/mol and a molecular formula of C6H12O6. It is well soluble in water, but its solubility in water varies greatly with temperature.
It is a sugar alcohol with half the sweetness of sucrose, and is naturally produced from glucose in the human body. The human kidneys produce about 2 g of inositol per day, and the organ in the human body with the highest concentration of inositol is the brain.
It plays an important role in binding neurotransmitters and some steroid hormones to their receptors.
Inositol was once considered a member of the B vitamin family and was called vitamin B8. However, it is not included in the essential nutrients list because it is produced from glucose in the human body.
Inositol has a cyclohexanol structure with six hydroxy groups attached to the cyclohexane ring. This structure allows inositol to function as part of many naturally occurring biomolecules.
Inositol is a meso compound and is optically inert because of its symmetry plane. Formerly called meso-inositol, it is now commonly referred to as myo-inositol because of the existence of other meso-isomers.
Other naturally occurring stereoisomers besides myo-inositol include scyllo-, muco-, D-chiro-, L-chiro-, and neo-inositol, which occur in nature only in very small quantities. Of these, L-tyroinositol and D-tyroinositol are, as their names suggest, the only enantiomeric pairs; all others are meso compounds.
The myoinositol isomer takes the chair-shaped structure as its most stable conformation.
Inositol is widely biosynthesized in plants, animals, and bacteria. It is synthesized in plant and animal cells. Natural inositol can be extracted from plants, but industrially, microbial fermentation is the primary method used. Industrially, it is mostly produced from cornstarch and wort.
Carbohydrates such as glucose and sucrose from plant materials are used as substrates for fermentation by yeast and bacteria. The product is then extracted and purified to yield inositol.
Solvent extraction, resin adsorption, chromatography, and membrane separation are used as extraction methods.
*Including some distributors, etc.
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Standard Process Inc. is an American nutritional supplement manufacturer that was originally established in Palmyra, Wisconsin in 1929. The company’s products include various herbal supplements which it markets under its MEDIHERB BRAND, as well as sport and performance-based whole food products marketed under its POSSIBLE brand. It also offers its STANDARD PROCESS VETERINARY FORMULAS brand supplements for cats, dogs, and horses. The company’s products are commonly used by high school and college sports teams, as well as educational institutions including the University of Western States (Oregon) and Texas Chiropractic College.
Based in Bayville, NY, SAE Manufacturing Specialties Corp. is an ISO-certified supplier and manufacturer of industrial equipment, chemicals, components, ordinance, electronics, and systems for industries ranging from aerospace to high tech to law enforcement. Examples of product offerings include raw materials, chemicals, and lubricants for industrial purposes to finished products such as security helmets for law enforcement, and military ordnances. SAE also provides research and development as well as technical support for other companies in similar industries.
NOW Foods was founded in 1968 and is based in Bloomingdale, Illinois. NOW Foods is a manufacturer and distributor of natural foods and supplements all over the globe. NOW Foods provides natural products with clean ingredients, comprehensive testing, and superior manufacturing. They empower healthy living by sharing knowledge on how to make small changes in daily life for a big impact on overall health like at-home workouts, self-care tips, and supplement education, Their product offerings include vitamins, minerals, organic beauty and sports nutrition products. NOW Foods, America’s private nutrition company meets consumers' need for affordable healthy food.
Rootcology is a supplier and distributor of dietary and nutritional supplements that was established in Las Vegas, Nevada in 2016, The company offers a range of thyroid health supplements, including for aiding in liver health, gut function, adrenal support, detoxification, and inflammatory disorders. It also offers personalized supplement kits tailored to customer needs as well as various books on thyroid health by Dr. Izabella Wentz, the founder of the company. The company’s products are commonly used and marketed within the alternative health, holistic health, and e-commerce sectors.
ChemUniverse, Inc. is a privately owned and operated specialty chemical provider that was founded in 2019.They are headquartered in Des Plaines, Illinois. They sell a wide range of chemicals, including amyl benzoate, naphthalene, pyridine, anethole, isoamyl benzoate, and many others which have different purposes. For instance, Amyl benzoate is a flavoring ingredient found in foods and perfumes while Naphthalene is a moth repellent and a component of various industrial solvents. They offer their services to customers looking for specialized or unique products and offer custom synthesis services to produce items that aren't already in their inventory.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Hard Eight Nutrition, LLC was founded in 2012 and is headquartered in Henderson, NV, as a manufacturer of nutritional supplements. The containers depict the capacity of the components contained therein, specifying the quantity of servings that can be prepared. The entire range of items the company offers may be conveniently accessed through our online store at BulkSupplements.com, with options accessible in quantities ranging from grams to metric tons. Before distribution, every supplement undergoes testing by an independent laboratory to guarantee the safety of all goods for consumption.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Designs for Health, Inc. is a nutritional products manufacturer and distributor that was established in Palm Coast, Florida in 1989. The company’s products include various branded dietary supplements for aiding in digestive health, immune function, joint support, and cardiovascular health. It also offers functional lab tests for measuring important biomarkers such as organic acids and cardiometabolic health. The company is NSF Certified for Sport, Non-GMO Project Verified, and USDA Organic certified, and its products are commonly used in private healthcare, professional sports, and fitness clubs.
Fairhaven Health is a manufacturer and distributor of women’s fertility and pregnancy products that was established in Bellingham, Washington in 2003. The company’s product lineup includes various branded items, such as its OVABOOST egg quality and ovarian function supplement for women with polycystic ovary syndrome (PCOS), FERTILECM cervical mucus production and endometrial health supplement, and FERTILAID essential nutrients and herbal supplement. The company’s products are commonly used in the healthcare sector via private providers and clinics, and are marketed in both physical and e-retail outlets.
Intimate Rose is an American manufacturer and distributor of women’s health products that was established in North Kansas City, Missouri in 2015. The company’s products include kegel exercise weights for pelvic floor exercises, pelvic wands for self-massage, and vaginal dilators in eight different sizes. It also offers supplements such as D-mannose, probiotics, and horny goat weed. The company is CE certified and FDA registered, and its products are commonly used in the healthcare industry. It also markets its products via physical retail as well as e-retail partners and outlets.
NutraTek Health Innovations Inc. is a Canadian manufacturer and distributor of nutritional supplements that was established in Raymond, Alberta in 2011. The company produces supplements that use its proprietary NutraTek™ mineral delivery technology, including omega-3 EPA and DHA fish oil supplements, micronutrient supplements, and inositol natural carbohydrates for regulating insulin and serotonin. It also offers personalized services and resources to its client organizations, such as gyms or boxing clubs. The company’s products are commonly used in military and healthcare sectors, as well as in Canada’s educational institutions.
Momentous is an American manufacturer and supplier of athletic nutrition products that was originally founded in Park City, Utah in 2017 as Amp Human before rebranding in 2019. The company’s products include dietary supplements such as essential plant-based proteins, whey protein, and collagen peptides. It also offers sports lotions, branded apparel, and other supplements for aiding brain health, sleep, and immune function. The company’s products are both Informed Sport and NSF Certified for Sport certification, and are commonly used in the sports medicine, military, and healthcare sectors.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | SAE Manufacturing Specialties Corp |
21.8%
|
2 | Standard Process Inc. |
16.2%
|
3 | NOW Foods |
7.8%
|
4 | Hard Eight Nutrition, LLC |
7.8%
|
5 | nacalai |
7.3%
|
6 | NutraTek Health Innovations Inc. |
6.7%
|
7 | Ingredients Online |
6.1%
|
8 | MilliporeSigma |
6.1%
|
9 | Rootcology |
5.6%
|
10 | Designs for Health, Inc. |
4.5%
|
Derivation Method
The ranking is calculated based on the click share within the inositol page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 6 | 85.7% |
Japan | 1 | 14.3% |