9 Isoproterenol Manufacturers in 2024
This section provides an overview for isoproterenol as well as their applications and principles. Also, please take a look at the list of 9 isoproterenol manufacturers and their company rankings. Here are the top-ranked isoproterenol companies as of November, 2024: 1.Cayman Chemical Company, 2.SynThink Research Chemicals, 3.Merck Millipore.
Table of Contents
What Is Isoproterenol?
Isoproterenol, also known as isoprenaline, is a drug that possesses an isopropylamine or catechol backbone. It is primarily used to treat atrioventricular block, bradycardia, and bronchial asthma due to its ability to act on beta-adrenergic receptors without affecting alpha-adrenergic receptors.
Uses of Isoproterenol
Isoproterenol selectively binds to β-adrenergic receptors, stimulating the sympathetic nervous system. This activation strengthens the heart's electrical signals, increasing heart rate and dilating peripheral blood vessels, which is beneficial in treating cardiac disorders like arrhythmia. It also relaxes smooth muscles, making it an effective bronchodilator for asthma and bronchospasm treatment.
Properties of Isoproterenol
Isoproterenol is a white powder or crystalline solid at room temperature. It has a chemical formula of C11H17NO3, a molecular weight of 211.258 g/mol, and a half-life of approximately 2 minutes post-absorption. The catecholamine structure of isoproterenol makes it a neurotransmitter mimetic.
Other Information on Isoproterenol
1. Effects of Isoproterenol
As a trace amine-associated receptor 1 agonist, isoproterenol's pharmacodynamic effects are similar to endogenous trace amines. Its nonselective circulatory system effects result from stimulation of beta1 and beta2 receptors, causing vasodilation and influencing blood pressure.
2. Structure-Activity Relationship of Isoproterenol
The isopropyl amino group in isoproterenol contributes to its selectivity for β-receptors, while the catechol hydroxyl group maintains sensitivity to metabolic enzymes.
3. Isoproterenol in Asthma Treatment
Isoproterenol, as an agonist of sympathetic β1 and β2 receptors, was widely used in asthma treatment before the development of β2-selective agonists like salbutamol.
4. Side Effects of Isoproterenol
Significant side effects of isoproterenol include a decrease in serum potassium levels and myocardial ischemia, particularly with the injectable form.
5. Related Substances to Isoproterenol
Catecholamines in isoproterenol serve as the backbone for various biological substances such as dopamine, levodopa, adrenaline, and noradrenaline.
List of 9 Isoproterenol Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Germany
- India
- Japan
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Cayman Chemical Company
Isoproterenol (hydrochloride)
Manufacturer Overview
Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
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Manufacturer Overview
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
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Tokyo Chemical Industry Co., Ltd.
Isoproterenol hydrochloride, Isoprenaline hydrochloride
Manufacturer Overview
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
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Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Merck Millipore
Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem
Company Overview
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
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APExBIO Technology LLC
Isoprenaline HCl
Company Overview
APExBIO Technology LLC is a distributor and supplier of molecular biology tools based in Houston, Texas, United States. The company's product portofolio includes various products such as small molecule inhibitors, compound libraries, fluorescent labels, modified nucleotides, and assay kits. The products are used in various areas such as cancer, immunology, neurosciences, apoptosis, and epigenetics researches. The company offers various supporting services such as analytical services, custom organic synthesis, custom peptide synthesis, and bioinformatics services.
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SynThink Research Chemicals
(S)-Isoprenaline; (S)-Isoproterenol
Distributor Overview
SynThink Research Chemicals, based in Pune, India, is a supplier of pharmaceutical research products to pharmaceutical and biotech companies as well as R&D labs at various research institutes and organizations. The company provides pharmaceutical reference standards, API impurities, metabolites, intermediates, building blocks and other research chemicals. It also provides custom synthesis services and contract research and development (CRO) services in the area of organic, pharmaceutical, and medicinal chemistry. The company offers custom packaging and worldwide shipping of in-stock products within 24 hours.
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AbMole BioScience
Isoprenaline hydrochloride
Distributor Overview
AbMole BioScience, headquartered in Houston, Texas, USA, is a supplier of high-purity life science reagents. The company specializes in kinase inhibitors tailored for laboratory research. Its extensive product range also encompasses of recombinant proteins, organoid molecules, fluorescent dyes, and compound libraries, catering to a diverse spectrum of life science research areas. It holds a collection of over 8,000 inhibitors targeting a range of key proteins such as HDAC, PI3K, and apoptosis regulators.
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Isoproterenol Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Cayman Chemical Company |
20.0%
|
| 2 | SynThink Research Chemicals |
13.3%
|
| 3 | Merck Millipore |
13.3%
|
| 4 | Tokyo Chemical Industry Co., Ltd. |
13.3%
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| 5 | MedChemExpress |
13.3%
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| 6 | AbMole BioScience |
6.7%
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| 7 | Witega Laboratorien Berlin-Adlershof GmbH |
6.7%
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| 8 | APExBIO Technology LLC |
6.7%
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| 9 | MilliporeSigma |
6.7%
|
Derivation Method
The ranking is calculated based on the click share within the isoproterenol page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
- Witega Laboratorien Berlin-Adlershof GmbH: 1993 (31 years ago)
- Cayman Chemical Company: 1980 (44 years ago)
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
Company with a History
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
- Cayman Chemical Company: 1980 (44 years ago)
- Witega Laboratorien Berlin-Adlershof GmbH: 1993 (31 years ago)
Isoproterenol Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Isoproterenol Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
2 | 40.0% |
Japan
|
1 | 20.0% |
Germany
|
1 | 20.0% |
India
|
1 | 20.0% |
