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This section provides an overview for aminophenol as well as their applications and principles. Also, please take a look at the list of 21 aminophenol manufacturers and their company rankings. Here are the top-ranked aminophenol companies as of December, 2024: 1.Spectrum Chemical Mfg. Corp., 2.ATAMAN Kimya A.S. INC., 3.Tokyo Chemical Industry Co., Ltd..
Table of Contents
Aminophenol is an organic compound where one hydrogen atom on the benzene ring of phenol is replaced by an amino group. It exists in three isomers: o-aminophenol (ortho-aminophenol), m-aminophenol (meta-aminophenol), and p-aminophenol (para-aminophenol), all solid at room temperature. The ortho form is white or pale yellow and needle-like, the meta form is white, and the para form is colorless platelet crystals, which gradually oxidize in air and turn brown.
The molecular weight of aminophenol is 109.13, with densities of 1.328 g/cm3 for ortho, 1.276 g/cm3 for meta, and 1.13 g/cm3 for para. Water solubility varies among the isomers: 2.0 x 103 mg/L for ortho, 26 g/L for meta, and 16 g/L for para.
All three isomers of aminophenol are important building blocks in synthetic organic chemistry. Specific uses include the synthesis of acetaminophen from p-aminophenol, heterocycle synthesis from o-aminophenol, and 3-(diethylamino)phenol from m-aminophenol, an intermediate in fluorescent dye synthesis. o-aminophenols are used by photographic developers, while m-aminophenols find applications as dyes, thermosensitive dyes, agrochemicals, and aramid fiber materials. p-aminophenols are used as antioxidants for rubber, oxidative dyes for fur, and also as a photographic developer like o-aminophenol.
o-aminophenol and p-aminophenol can be produced by reducing a mixture of o-nitrophenol and p-nitrophenol, obtained from the nitration of phenol. The synthesis of m-aminophenol requires a different route, such as melting 3-aminobenzene sulfonic acid with sodium hydroxide or substituting resorcinol with ammonium hydroxide.
o-Aminophenol forms intra- and intermolecular hydrogen bonds. Its amino groups can be diazotized for dye synthesis, and diazotized o-aminophenol compounds are useful as tridentate ligands to form metal complexes.
Aminophenols are available as reagent products for research and development, as well as oxidative
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Cambridge Isotope Laboratories (CIL) established in 1981, is a global supplier of stable isotopes and labeled compounds, headquartered in the United States. The company provides of products for research, environmental analysis, and medical applications.Their comprehensive product offerings include isotopically labeled standards, biochemicals, and gases, catering to many industries and scientific communities, with partnerships worldwide. They specializes in the process of labeling biochemical and organic compounds with highly enriched, stable (nonradioactive) isotopes of carbon, hydrogen, nitrogen and oxygen.
MedKoo Biosciences, Inc. is an American manufacturer of biochemical reagents established in 2009 and based in Morrisville, North Carolina. Specializing in small molecule drugs for laboratory use, the company offers a wide range of products including apoptosis inducers, anticancer reagents, epigenetic modulators, and various pharmaceutical related chemicals. These have applications in various fields including microbiology, stem cell research, endocrinology, and epigenetics. MedKoo Biosciences also provides R&D services to client biotechnology, biomedical, and pharmaceutical companies, as well as academic institutions.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
LGC Standards Ltd., established in 1842, is a global British manufacturer and supplier of reference standards, headquartered in Teddington, Middlesex, with offices in 20 countries worldwide. As a subsidiary of LGC Group, the United Kingdom’s National Measurement Institute, LGC Standards also serves as the Government Chemist, providing expert opinions based on independent chemical and bioanalytical measurements. Under the business unit LGC Industrial, the company offers industrial measurement tools. Additionally, their subsidiaries, including Toronto Research Chemicals Inc (TRC) of Canada, LGC Mikromol™, and Dr. Ehrenstorfer™ of Germany, develop research tools, standards for pharmaceutical quality control, and reference materials for food and environmental analysis.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
SVAK Life Sciences, established in 2016 and located in Hyderabad, Telangana, is a contract research organization that provides research services to the pharmaceutical and biotechnology industries. The company offers services such as custom synthesis of pharmaceutical Impurities, reference standards, end-to-end API process development, and cost improvement process development for existing intermediates/API, serving pharmaceutical companies, specialty chemical manufacturers, universities, and other research institutions. Its product line includes abacavir, agomelatine, amlodipine, atorvastatin, and azilsartan, serving known companies like companies like Dr. Reddy's, Alembic, Mylan, Biocon, and Jubilant Life Sciences.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Carl Roth GmbH + Co. KG, established in 1879 and headquartered in Karlsruhe, Germany, is a manufacturer, distributor, and supplier of laboratory equipment, life science products, and chemicals. Their extensive product range encompasses analytical instruments, biological safety cabinets, heating mantles, pH meters, centrifuges, thermometers, and various chemicals. Their products support and facilitate laboratory research, analysis, and experimentation across various industries such as pharmaceutical, chemical, and environmental sectors. The company is certified according to DIN EN ISO 9001:2015 and DIN EN ISO 14001:2015.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
AdooQ BioScience, founded in 2006 and headquartered in Irvine, California, is a supplier specializing in purity inhibitors, chemical probes and reference compounds. The company's product portfolio includes inhibitors for signaling pathways, epigenetics, apoptosis, stem cells, and proteins. These products serve as tools for researchers in academia as well as the biotechnology and pharmaceutical industries, facilitating the execution of experiments, exploration of diseases, and the potential development of treatments and therapies. The company has established over 25 distributors in 30 different countries, along with service networks spanning five continents, thereby ensuring a worldwide reach.
Selleck Chemicals, founded in 2005 in Houston, Texas, USA is a supplier of biotechnology equipment. The company specializes in the supply of small molecule inhibitors, therapeutic antibodies, lab reagents, peptides and compound screening libraries. It supplies over 120,000 inhibitors, required for the study of cell signaling pathways. It helps drug discovery and systems biology researchstudies by supplying High Throughput Screening and High Content Screening equipment. With 10,000 customers on board, the company has headquarters in the United States, Asia, and Europe, and 38 distributors worldwide.
Ataman Kimya, established in 2006, is a distributor of chemicals based in Istanbul, Turkey. Their wide range of products includes detergents, cosmetics, disinfectants, pharmaceutical chemicals, and water treatment chemicals. They also offer textile, leather, paper, and mining chemicals. These chemicals, such as hydrogenated castor oils, ethanol, and butylene glycol, find applications in various industries, such as personal care, household cleaning, fragrance, coatings, and agriculture. The company also offers custom blending to meet specific requirements.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Spectrum Chemical Mfg. Corp. |
25.0%
|
| 2 | ATAMAN Kimya A.S. INC. |
8.9%
|
| 3 | Tokyo Chemical Industry Co., Ltd. |
8.9%
|
| 4 | KAJAY REMEDIES PVT. LTD |
7.1%
|
| 5 | MilliporeSigma |
7.1%
|
| 6 | MedKoo Biosciences, Inc. |
5.4%
|
| 7 | LobaChemie Pct.Ltd. |
5.4%
|
| 8 | Cambridge Isotope Laboratories, Inc. |
5.4%
|
| 9 | Carl Roth GmbH + Co. KG |
5.4%
|
| 10 | nacalai |
5.4%
|
Derivation Method
The ranking is calculated based on the click share within the aminophenol page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 30.8% |
|
India
|
2 | 15.4% |
|
Japan
|
2 | 15.4% |
|
United Kingdom
|
1 | 7.7% |
|
Canada
|
1 | 7.7% |
|
Germany
|
1 | 7.7% |
Netherlands
|
1 | 7.7% |
Spain
|
1 | 7.7% |
